Esophageal Subepithelial Fibrosis and Hyalinization Are Features of Eosinophilic Esophagitis
نویسنده
چکیده
performed to 16 foods and 38 inhalant allergens. Patch testing to foods was also performed. IgE-mediated allergy was diagnosed if either serum-specific IgE or skinprick test results were positive, whereas non–IgE-mediated allergy was diagnosed if a positive patch test result was found. A streptavidin-based immunoassay was performed to determine the presence of cross-reactive carbohydrate determinants and Helicobacter pylori.
منابع مشابه
Esophageal subepithelial fibrosis and hyalinization are features of eosinophilic esophagitis.
BACKGROUND AND OBJECTIVE Eosinophilic esophagitis (EE) is characterized by marked esophageal mucosal eosinophilia on histological examination. Although the clinical and histological features of EE are increasingly recognized, the overlap of clinical symptoms and histological findings with gastroesophageal reflux disease (GERD) can lead to diagnostic difficulty. In children with EE we sought to ...
متن کاملEsophageal Subepithelial Fibrosis and Hyalinization Are Features of Eosinophilic Esophagitis
performed to 16 foods and 38 inhalant allergens. Patch testing to foods was also performed. IgE-mediated allergy was diagnosed if either serum-specific IgE or skinprick test results were positive, whereas non–IgE-mediated allergy was diagnosed if a positive patch test result was found. A streptavidin-based immunoassay was performed to determine the presence of cross-reactive carbohydrate determ...
متن کاملEsophageal Subepithelial Fibrosis and Hyalinization Are Features of Eosinophilic Esophagitis
performed to 16 foods and 38 inhalant allergens. Patch testing to foods was also performed. IgE-mediated allergy was diagnosed if either serum-specific IgE or skinprick test results were positive, whereas non–IgE-mediated allergy was diagnosed if a positive patch test result was found. A streptavidin-based immunoassay was performed to determine the presence of cross-reactive carbohydrate determ...
متن کاملEsophageal subepithelial fibrosis in children with eosinophilic esophagitis.
OBJECTIVES Esophageal subepithelial fibrosis has been reported in adults with eosinophilic esophagitis (EE). Our goal was to determine the prevalence of esophageal fibrosis in children with EE, to determine whether it is specific for EE, and to correlate it with clinical and pathological features. PATIENTS AND METHODS Twenty-one children with EE, 7 with eosinophilic gastroenteritis, 6 with ga...
متن کاملRelationships between eosinophilic inflammation, tissue remodeling, and fibrosis in eosinophilic esophagitis.
The clinical and pathologic features of eosinophilic esophagitis (EE) include extensive tissue remodeling. Increasing evidence supports a key role for the eosinophil in multiple aspects of the esophageal remodeling and fibrosis seen in this allergic disease. This article reviews the clinical implications of esophageal remodeling and fibrosis in EE and discusses the possible pathogenic mechanism...
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